TRANSCRIPTION TARGET GENE SET ENRICHMENT RESULTS

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched transcription factor targets (TFT), number of Entrez IDs in your user data set for the TFT, the corresponding Entrez IDs, and the statistics for the enriched TF.
The statistic column lists:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

TFT	#Gene	EntrezGene	Statistics
hsa_V$E2F_Q4	13	9824 8318 9768 5427 5888 81620 116028 1869 6241 990 9088 983 2146	C=231;O=13;E=0.48;R=26.97;rawP=2.43e-15;adjP=1.20e-13
hsa_V$E2F_Q6	13	9824 8318 9768 5427 5888 81620 116028 1869 6241 990 9088 983 2146	C=229;O=13;E=0.48;R=27.20;rawP=2.17e-15;adjP=1.20e-13
hsa_V$E2F1_Q6	12	9824 9768 5427 81620 116028 1869 6241 1174 990 9088 983 2146	C=228;O=12;E=0.48;R=25.22;rawP=6.79e-14;adjP=1.68e-12
hsa_V$E2F1DP1RB_01	12	9824 9768 5427 5888 81620 116028 1869 6241 990 9088 983 2146	C=228;O=12;E=0.48;R=25.22;rawP=6.79e-14;adjP=1.68e-12
hsa_V$E2F1DP1_01	11	9824 9768 5427 116028 1869 6241 1174 990 9088 983 2146	C=231;O=11;E=0.48;R=22.82;rawP=2.35e-12;adjP=2.91e-11
hsa_V$E2F1DP2_01	11	9824 9768 5427 116028 1869 6241 1174 990 9088 983 2146	C=231;O=11;E=0.48;R=22.82;rawP=2.35e-12;adjP=2.91e-11
hsa_V$E2F_02	11	9824 9768 5427 116028 1869 6241 1174 990 9088 983 2146	C=231;O=11;E=0.48;R=22.82;rawP=2.35e-12;adjP=2.91e-11
hsa_V$E2F4DP2_01	11	9824 9768 5427 116028 1869 6241 1174 990 9088 983 2146	C=231;O=11;E=0.48;R=22.82;rawP=2.35e-12;adjP=2.91e-11
hsa_V$E2F4DP1_01	11	9824 9768 5427 116028 1869 6241 1174 990 9088 983 2146	C=236;O=11;E=0.49;R=22.34;rawP=2.97e-12;adjP=3.27e-11
hsa_V$E2F_Q6_01	11	9824 8318 9768 5427 5888 116028 1869 6241 990 9088 2146	C=239;O=11;E=0.50;R=22.05;rawP=3.40e-12;adjP=3.37e-11

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).